Amyloid beta Precusor Protein Antibody (APP) | F51499-0.08ML

Amyloid beta Precusor Protein Antibody (APP) | F51499-0.08ML | Gentaur US, UK & Europe Disrtribition

Family: Primary antibody

Formulation: In 1X PBS, pH 7.4, with 0.09% sodium azide

Format: Antigen affinity purified

Clone: N/A

Host Animal: Rabbit

Clonality: Polyclonal (rabbit origin)

Species Reactivity: Human

Application: WB, ELISA

Buffer: N/A

Limitation: This Amyloid beta precusor protein antibody is available for research use only.

Purity: Antigen affinity

Description: APP is a cell surface receptor and transmembrane precursor protein that is cleaved by secretases to form a number of peptides. Some of these peptides are secreted and can bind to the acetyltransferase complex APBB1/TIP60 to promote transcriptional activation, while others form the protein basis of the amyloid plaques found in the brains of patients with Alzheimer disease. Mutations in this gene have been implicated in autosomal dominant Alzheimer disease and cerebroarterial amyloidosis (cerebral amyloid angiopathy).

Immunogen: A portion of amino acids 735-763 from the human protein was used as the immunogen for this Amyloid beta precusor protein antibody.

Storage: Aliquot the Amyloid beta precusor protein antibody and store frozen at -20 °C or colder. Avoid repeated freeze-thaw cycles.