Description
Amyloid beta Antibody / APP | V8733-20UG | Gentaur US, UK & Europe Disrtribition
Family: Primary antibody
Formulation: 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide
Format: Purified
Clone: APP/3345
Host Animal: Mouse
Clonality: Monoclonal (mouse origin)
Species Reactivity: Human
Application: IF, FACS, IHC-P
Buffer: N/A
Limitation: This Amyloid Beta antibody is available for research use only.
Purity: Protein G affinity chromatography
Description: Proteolytic cleavage of the Amyloid protein precursor (APP) gives rise to the /A4 Amyloid protein. This protein is involved in the formation of neurofibrillary tangles and plaques that characterize the senile plaques of Alzheimer s patients. APLP1 (Amyloid precursor-like protein 1) and APLP2 are structurally similar to APP. Human APLP2 is a membrane-bound sperm protein that contains a region highly homologous to the transmembrane-cytoplasmic domains of APP found in brain plaques of Alzheimer s disease patients.
Immunogen: A portion of amino acids 578-680 from the human protein was used as the immunogen for the Amyloid Beta antibody.
Storage: Store the Amyloid Beta antibody at 2-8oC (with azide) or aliquot and store at -20 °C or colder (without azide).
