Amyloid beta Antibody / APP | V8732-20UG

Amyloid beta Antibody / APP | V8732-20UG | Gentaur US, UK & Europe Disrtribition

Family: Primary antibody

Formulation: 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide

Format: Purified

Clone: APP/3343

Host Animal: Mouse

Clonality: Monoclonal (mouse origin)

Species Reactivity: Human

Application: IHC-P

Buffer: N/A

Limitation: This Beta Amyloid antibody is available for research use only.

Purity: Protein G affinity chromatography

Description: Proteolytic cleavage of the Amyloid protein precursor (APP) gives rise to the /A4 Amyloid protein. This protein is involved in the formation of neurofibrillary tangles and plaques that characterize the senile plaques of Alzheimer s patients. APLP1 (Amyloid precursor-like protein 1) and APLP2 are structurally similar to APP. Human APLP2 is a membrane-bound sperm protein that contains a region highly homologous to the transmembrane-cytoplasmic domains of APP found in brain plaques of Alzheimer s disease patients.

Immunogen: A portion of amino acids 578-680 from the human protein was used as the immunogen for the Beta Amyloid antibody.

Storage: Store the Beta Amyloid antibody at 2-8oC (with azide) or aliquot and store at -20 °C or colder (without azide).