Description
AMACR Polyclonal Antibody | E-AB-40482 | Gentaur US, UK & Europe Disrtribition
Reactivity: Mouse, Rat
Host: Rabbit
Isotype: IgG
Application: WB, IHC
Research Area: Cell Biology, Metabolism, Signal Transduction
Background: AMACR(Alpha-methylacyl-CoA racemase) belongs to the CaiB/BaiF CoA-transferase family. It is a mitochondrial and peroxisomal enzyme that catalyzes the conversion of 2R stereoisomers of phytanic and pristanic acid to their S counterparts. AMACR has previously been shown to be a highly sensitive marker for colorectal and clinically localized prostate cancer (PCa). However, AMACR expression is down-regulated at the transcript and protein level in hormone-refractory metastatic PCa, suggesting a hormone-dependent expression of AMACR. It has 3 isoforms produced by alternative splicing. Defects in AMACR are the cause of alpha-methylacyl-CoA racemase deficiency (AMACRD) and congenital bile acid synthesis defect type 4 (CBAS4).
Lead Time: Order now, ship in 3 day
Concentration: 1mg/mL
Storage: Store at -20℃. Avoid freeze / thaw cycles.
Immunogen: Recombinant Mouse Alpha-methylacyl-CoA racemase protein
Buffer: PBS with 0.05% Proclin300, 50% glycerol, pH7.3.
Purification: Antigen Affinity Purification
Dilution: WB 1:1000-1:3000 IHC 1:100-1:200
Conjugation: N/A
Calculated Molecular Weight: 42 kDa
Observed Molecular Weight: 40 kDa
Clonality: Polyclonal
