AMACR / p504S Antibody (Prostate Cancer Marker) | V3237SAF-100UG

AMACR / p504S Antibody (Prostate Cancer Marker) | V3237SAF-100UG | Gentaur US, UK & Europe Disrtribition

Family: Primary antibody

Formulation: 1 mg/ml in 1X PBS; BSA free, sodium azide free

Format: Purified

Clone: AMACR/1723

Host Animal: Mouse

Clonality: Monoclonal (mouse origin)

Species Reactivity: Human

Application: WB, IHC-P

Buffer: N/A

Limitation: This AMACR antibody is available for research use only.

Purity: Protein G affinity chromatography

Description: AMACR, also known as p504S is an enzyme that is involved in bile acid biosynthesis and beta-oxidation of branched-chain fatty acids. It is expressed in cells of premalignant high-grade prostatic intraepithelial neoplasia (HGPIN) and prostate adenocarcinoma. The majority of the carcinoma cells show a distinct granular cytoplasmic staining reaction. AMACR is present at low or undetectable levels in glandular epithelial cells of normal prostate and benign prostatic hyperplasia. A spotty granular cytoplasmic staining is seen in a few cells of the benign glands.

Immunogen: A recombinant human protein was used as the immunogen for the AMACR antibody.

Storage: Store the AMACR antibody at 2-8oC (with azide) or aliquot and store at -20 °C or colder (without azide).