Description
AMACR Antibody | F40477-0.4ML | Gentaur US, UK & Europe Disrtribition
Family: Primary antibody
Formulation: In 1X PBS, pH 7.4, with 0.09% sodium azide
Format: Antigen affinity purified
Clone: N/A
Host Animal: Rabbit
Clonality: Polyclonal (rabbit origin)
Species Reactivity: Human
Application: FACS, IF, WB, IHC, ELISA
Buffer: N/A
Limitation: This AMACR antibody is available for research use only.
Purity: Antigen affinity
Description: This gene encodes a racemase. The encoded enzyme interconverts pristanoyl-CoA and C27-bile acylCoAs between their (R)- and (S)-stereoisomers. The conversion to the (S)-stereoisomers is necessary for degradation of these substrates by peroxisomal beta-oxidation. Encoded proteins from this locus localize to both mitochondria and peroxisomes. Mutations in this gene may be associated with adult-onset sensorimotor neuropathy, pigmentary retinopathy, and adrenomyeloneuropathy due to defects in bile acid synthesis. Alternatively spliced transcript variants have been described.
Immunogen: A portion of amino acids 323-351 from the human protein was used as the immunogen for this AMACR antibody.
Storage: Aliquot the AMACR antibody and store frozen at -20 °C or colder. Avoid repeated freeze-thaw cycles.
