AMACR Antibody | F40477-0.08ML

AMACR Antibody | F40477-0.08ML | Gentaur US, UK & Europe Disrtribition

Family: Primary antibody

Formulation: In 1X PBS, pH 7.4, with 0.09% sodium azide

Format: Antigen affinity purified

Clone: N/A

Host Animal: Rabbit

Clonality: Polyclonal (rabbit origin)

Species Reactivity: Human

Application: FACS, IF, WB, IHC, ELISA

Buffer: N/A

Limitation: This AMACR antibody is available for research use only.

Purity: Antigen affinity

Description: This gene encodes a racemase. The encoded enzyme interconverts pristanoyl-CoA and C27-bile acylCoAs between their (R)- and (S)-stereoisomers. The conversion to the (S)-stereoisomers is necessary for degradation of these substrates by peroxisomal beta-oxidation. Encoded proteins from this locus localize to both mitochondria and peroxisomes. Mutations in this gene may be associated with adult-onset sensorimotor neuropathy, pigmentary retinopathy, and adrenomyeloneuropathy due to defects in bile acid synthesis. Alternatively spliced transcript variants have been described.

Immunogen: A portion of amino acids 323-351 from the human protein was used as the immunogen for this AMACR antibody.

Storage: Aliquot the AMACR antibody and store frozen at -20 °C or colder. Avoid repeated freeze-thaw cycles.