Description
Alpha Catenin Antibody | V3202SAF-100UG | Gentaur US, UK & Europe Disrtribition
Family: Primary antibody
Formulation: 1 mg/ml in 1X PBS; BSA free, sodium azide free
Format: Purified
Clone: 1G5
Host Animal: Mouse
Clonality: Monoclonal (mouse origin)
Species Reactivity: Human
Application: FACS, IF, WB
Buffer: N/A
Limitation: This Alpha Catenin antibody is available for research use only.
Purity: Protein G affinity chromatography
Description: Recognizes a protein of 102kDa, identified as Catenin, alpha-1. Catenins comprise a large family of Ca2+-dependent, homotypic cell-cell adhesion molecules that play important roles in development, epithelial cell polarity and tumor progression. Alpha-Catenin is a key regulator of actin dynamics in cell-cell adhesion. During cell-cell adhesion, alpha-Catenin forms a heterodimer with beta-Catenin and links the cadherins to actin associated with the cytoskeleton. Alpha-Catenin also regulates the beta-Catenin signaling in various cells. It displays the tumor suppressor activity and is found to be down regulated in some forms of breast cancer.
Immunogen: A human fusion protein was used as the immunogen for the Alpha Catenin antibody.
Storage: Store the Alpha Catenin antibody at 2-8oC (with azide) or aliquot and store at -20 °C or colder (without azide).
