Description
Alpha Actin Antibody / ACTA2 (smooth muscle) | V2837-20UG | Gentaur US, UK & Europe Disrtribition
Family: Primary antibody
Formulation: 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide
Format: Purified
Clone: ACTA2/791
Host Animal: Mouse
Clonality: Monoclonal (mouse origin)
Species Reactivity: Human, Rat
Application: IF, IHC-P
Buffer: N/A
Limitation: This Alpha Smooth Muscle Actin antibody is available for research use only.
Purity: Protein G affinity chromatography
Description: Actin is a major component of the cytoskeleton and is present in most cell types. It is highly specific to actin from smooth muscles. This mAb does not stain cardiac or skeletal muscle; however, it does stain myofibroblasts and myoepithelial cells. This antibody could be used together with anti-muscle specific actin and myogenin in making a diagnosis of smooth muscle and skeletal muscle tumors. In most cases of rhabdomyosarcoma, this antibody yields negative results whereas anti-muscle specific actin and myogenin are positive. Leiomyosarcomas are positive only with anti-muscle specific actin and anti-smooth muscle actin and are negative with anti-myogenin.
Immunogen: Recombinant full-length human protein was used as the immunogen for the Alpha Smooth Muscle Actin antibody.
Storage: Store the Alpha Smooth Muscle Actin antibody at 2-8oC (with azide) or aliquot and store at -20 °C or colder (without azide).
