Description
ALDH2 Antibody | F40217-0.4ML | Gentaur US, UK & Europe Disrtribition
Family: Primary antibody
Formulation: In 1X PBS, pH 7.4, with 0.09% sodium azide
Format: Purified
Clone: 138CT22.3.8
Host Animal: Mouse
Clonality: Monoclonal (mouse origin)
Species Reactivity: Human
Application: IHC, FACS, IF, WB, ELISA
Buffer: N/A
Limitation: This ALDH2 antibody is available for research use only.
Purity: Purified
Description: This protein belongs to the aldehyde dehydrogenase family of proteins. Aldehyde dehydrogenase is the second enzyme of the major oxidative pathway of alcohol metabolism. Two major liver isoforms of this enzyme, cytosolic and mitochondrial, can be distinguished by their electrophoretic mobilities, kinetic properties, and subcellular localizations. Most Caucasians have two major isozymes, while approximately 50% of Orientals have only the cytosolic isozyme, missing the mitochondrial isozyme. A remarkably higher frequency of acute alcohol intoxication among Orientals than among Caucasians could be related to the absence of the mitochondrial isozyme. This gene encodes a mitochondrial isoform, which has a low Km for acetaldehydes, and is localized in mitochondrial matrix.
Immunogen: This ALDH2 antibody was produced from a mouse immunized with ALDH2 recombinant protein.
Storage: Aliquot the ALDH2 antibody and store frozen at -20 °C or colder. Avoid repeated freeze-thaw cycles.
