AKR7A2 Polyclonal Antibody | E-AB-60266

AKR7A2 Polyclonal Antibody | E-AB-60266 | Gentaur US, UK & Europe Disrtribition

Reactivity: Human, Mouse

Host: Rabbit

Isotype: IgG

Application: WB, IHC, IF

Research Area: Metabolism, Neuroscience, Signal Transduction

Background: The protein encoded by this gene belongs to the aldo/keto reductase (AKR) superfamily and AKR7 family, which are involved in the detoxification of aldehydes and ketones. The AKR7 family consists of 3 genes that are present in a cluster on the p arm of chromosome 1. This protein, thought to be localized in the golgi, catalyzes the NADPH-dependent reduction of succinic semialdehyde to the endogenous neuromodulator, gamma-hydroxybutyrate. It may also function as a detoxication enzyme in the reduction of aflatoxin B1 and 2-carboxybenzaldehyde. Alternative splicing results in multiple transcript variants.

Lead Time: 7~10 days

Concentration: 1 mg/mL

Storage: Store at -20°C. Avoid freeze / thaw cycles.

Immunogen: Recombinant fusion protein of human AKR7A2 (NP_003680.2).

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Purification: Affinity purification

Dilution: WB 1:500-1:2000 IHC 1:50-1:200 IF 1:10-1:100

Conjugation: Unconjugated

Calculated Molecular Weight: 39 kDa

Observed Molecular Weight: 35 kDa

Clonality: N/A