AKR1B1 Antibody / Aldose reductase | V3987-20UG

AKR1B1 Antibody / Aldose reductase | V3987-20UG | Gentaur US, UK & Europe Disrtribition

Family: Primary antibody

Formulation: 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide

Format: Purified

Clone: CPTC-AKR1B1-2

Host Animal: Mouse

Clonality: Monoclonal (mouse origin)

Species Reactivity: Human

Application: WB, IF, IHC-P

Buffer: N/A

Limitation: This AKR1B1 antibody is available for research use only.

Purity: Protein G affinity chromatography

Description: AKR1B1, also deisgnated as aldose reductase, is a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. This protein catalyzes the reduction of a number of aldehydes, including the aldehyde form of glucose, and is thereby implicated in the development of diabetic complications by catalyzing the reduction of glucose to sorbitol. It has also been shown to have decreased expression in adrenocortical cancer, and possibly play a role in adrenal tumorigenesis. It has been suggested that AKR1B1 could be investigated as a marker of malignancy for adrenal tumor diagnosis.

Immunogen: Recombinant protein was used as the immunogen for this AKR1B1 antibody.

Storage: Store the AKR1B1 antibody at 2-8oC (with azide) or aliquot and store at -20 °C or colder (without azide).