Description
AIFM1 Antibody / AIF / Apoptosis-Inducing Factor | F54468-0.08ML | Gentaur US, UK & Europe Disrtribition
Family: Primary antibody
Formulation: In 1X PBS, pH 7.4, with 0.09% sodium azide
Format: Purified
Clone: N/A
Host Animal: Rabbit
Clonality: Polyclonal (rabbit origin)
Species Reactivity: Human
Application: FACS, IHC-P, WB, IF
Buffer: N/A
Limitation: This AIF antibody is available for research use only.
Purity: Antigen affinity purified
Description: AIFM1 is a flavoprotein essential for nuclear disassembly in apoptotic cells that is found in the mitochondrial intermembrane space in healthy cells. Induction of apoptosis results in the translocation of this protein to the nucleus where it effects chromosome condensation and fragmentation. In addition, this protein induces mitochondria to release the apoptogenic proteins cytochrome c and caspase-9.
Immunogen: A portion of amino acids 70-98 from the human protein was used as the immunogen for the AIF antibody.
Storage: Aliquot the AIF antibody and store frozen at -20 °C or colder. Avoid repeated freeze-thaw cycles.
