AF647 Anti-Mouse CD90.2 Antibody | DL21102F-1

AF647 Anti-Mouse CD90.2 Antibody | DL21102F-1 | Gentaur US, UK & Europe Disrtribition

Synonyms: Thy-1.2 membrane glycoprotein,Thy1.2,Thy-1.2 antigen,CD90.2,Thy-1.2

Reactivity: Mouse

Host: Rat

Application: FCM

Background: CD90.2 is a 25-35 kD immunoglobulin superfamily member also known as Thy1.2. It is expressed on hematopoietic stem cells and neurons, all thymocytes, and peripheral T cells in Thy1.2 bearing mouse strains (Balb/c, CBA/J, C3H/He, C57BL/-, DBA, NZB/-) . CD90.2 is a glycosylphosphatidylinositol (GPI) -anchored membrane glycoprotein involved in signal transduction. CD90.2 is involved in costimulation of lymphocyte proliferation and induction of hematopoietic stem cells differentiation. CD90.2 has been shown to interact with CD45. The 30H12 antibody has been reported to induce Ca2+ flux in thymocytes and, in combination with antibody against the CD3/TCR complex, promote thymocyte apoptosis and inhibit CD3-mediated proliferative responses of mature T lymphocytes.

Concentration: 0.5 mg/mL

Conjugation: AF647

Buffer: PBS with 0.05% Proclin300, 1% BSA

Isotype: Rat IgG2b, κ

Storage: Store at 2~8°C and protected from prolonged exposure to light. Do not freeze.