Description
AF647 Anti-Mouse CD183/CXCR3 Antibody | DL21410F-1 | Gentaur US, UK & Europe Disrtribition
Synonyms: C-X-C chemokine receptor type 3,Cxcr3,CXC-R3,CXCR-3,Interferon-inducible protein 10 receptor,IP-10 receptor,CD183/CXCR3
Reactivity: Mouse
Host: Armenian Hamster
Application: FCM
Background: CD183/CXCR3, also known as CXCR3, is a member of the C-X-C chemokine family, characterized by a pair of cysteine residues separated by a single amino acid. CXCR3 is a 38 kD seven pass transmembrane receptor coupled to G-protein. It mediates Ca2+ mobilization and chemotaxis in response to C-X-C chemokines, such as IP10 (CXCL10), MIG (CXCL9), I-TAC (CXCL11) and PF4 (CXCL4) . CXCR3 is expressed primarily on activiated T lymphocytes, NK cells, and some epithelial cells and endothelial cells. It is not expressed on B cells, monocytes or granulocytes.
Concentration: 0.5 mg/mL
Conjugation: AF647
Buffer: PBS with 0.05% Proclin300, 1% BSA
Isotype: Armenian Hamster IgG
Storage: Store at 2~8°C and protected from prolonged exposure to light. Do not freeze.
