AF647 Anti-Human CD28 Antibody | DL22145F-2

AF647 Anti-Human CD28 Antibody | DL22145F-2 | Gentaur US, UK & Europe Disrtribition

Synonyms: PAS2,MNS,HGpMiX,GYPA,GPSAT

Reactivity: Human

Host: Mouse

Application: FCM

Background: CD28 is a 44 kD disulfide-linked homodimeric type I glycoprotein. It is a member of the immunoglobulin superfamily and is also known as T44 or Tp44. CD28 is expressed on most T lineage cells, NK cell subsets, and plasma cells. CD28 binds both CD80 and CD86 using a highly conserved motif MYPPY in the CDR3-like loop. CD28 is considered a major co-stimulatory molecule, inducing T lymphocyte activation and IL-2 synthesis, and preventing cell death. In vitro studies indicate that ligation of CD28 on T cells by CD80 and CD86 on antigen presenting cells provides a costimulatory signal required for T cell activation and proliferation.

Concentration: N/A

Conjugation: AF647

Buffer: PBS with 0.05% Proclin300, 1% BSA

Isotype: Mouse IgG1, κ

Storage: Store at 2~8°C and protected from prolonged exposure to light. Do not freeze.