Description
AF647 Anti-Human CD16 Antibody | DL22730F-4 | Gentaur US, UK & Europe Disrtribition
Synonyms: FcγRIII,Fc gamma receptor,Fc gamma receptor 3
Reactivity: Human
Host: Mouse
Application: FCM
Background: CD16 is a 60 kD highly glycosylated protein. It is a member of the Ig superfamily and is also known as B7-1, B7, and Ly-53. CD16 is constitutively expressed on dendritic cells and monocytes/macrophages, and inducibly expressed on activated B and T cells. The ligation of CD28 on T cells with CD16 and CD86 (B7-2) on antigen presenting cells (such as dendritic cells, macrophages, and B cells) elicits co-stimulation of T cells resulting in enhanced cell activation, proliferation, and cytokine production. CD16 appears to be expressed later in the immune response than CD86. CD16 can also bind to CD152, also known as CTLA-4, to deliver an inhibitory signal to T cells.
Concentration: N/A
Conjugation: AF647
Buffer: PBS with 0.05% Proclin300, 1% BSA
Isotype: Mouse IgG1, κ
Storage: Store at 2~8°C and protected from prolonged exposure to light. Do not freeze.
