Description
AF488 Anti-Mouse CD45.2 Antibody | DL21540F-3 | Gentaur US, UK & Europe Disrtribition
Synonyms: Ly-5.2, LCA
Reactivity: Mouse
Host: Mouse
Application: FCM
Background: CD45.2 is an alloantigen of CD45, expressed by Ly5.2 bearing mouse strains (e.g., A, AKR, BALB/c, CBA/Ca, CBA/J, C3H/He, C57BL, C57BR, C57L, C58, DBA/1, DBA/2, NZB, SWR, 129) . CD45, a member of the protein tyrosine phosphatase (PTP) family, is a 180-240 kD glycoprotein expressed on all hematopoietic cells except mature erythrocytes and platelets. There are multiple isoforms in the mouse that play key roles in TCR and BCR signal transduction. These isoforms are very specific to the activation and maturation states of the cell as well as specific cell type. The primary ligands for CD45 are galectin-1, CD2, CD3, CD4, TCR, CD22, and Thy-1.
Concentration: 0.5 mg/mL
Conjugation: AF488
Buffer: PBS with 0.05% Proclin300, 1% BSA
Isotype: Mouse IgG2a, κ
Storage: Store at 2~8°C and protected from prolonged exposure to light. Do not freeze.
