Description
AF488 Anti-Mouse CD117 Antibody | DL22618F-3 | Gentaur US, UK & Europe Disrtribition
Synonyms: Mast/stem cell growth factor receptor Kit,Kit,SCFR,Proto-oncogene c-Kit,Tyrosine-protein kinase Kit,CD117
Reactivity: Mouse
Host: Rat
Application: FCM
Background: CD117 is a 145 kD immunoglobulin superfamily member also known as c-Kit and stem cell factor receptor (SCFR) . It is a transmembrane tyrosine-kinase receptor that binds the c-Kit ligand (also known as steel factor, stem cell factor, and mast cell growth factor) . CD117 is expressed on hematopoietic stem cells (including multipotent hematopoietic stem cells, progenitors committed to myeloid and/or erythroid lineages, and T and B cell precursors), mast cells, and acute myeloid leukemia (AML) cells. CD117 interaction with its ligand is critical for the development of hematopoietic stem cells.
Concentration: 0.5 mg/mL
Conjugation: AF488
Buffer: PBS with 0.05% Proclin300, 1% BSA
Isotype: Rat IgG2b, κ
Storage: Store at 2~8°C and protected from prolonged exposure to light. Do not freeze.
