Description
AF488 Anti-Human CD45RA Antibody | DL20722F-1 | Gentaur US, UK & Europe Disrtribition
Synonyms: Receptor-type tyrosine-protein phosphatase C,Ptprc,L-CA,Ly-5,T200,CD45
Reactivity: Human
Host: Mouse
Application: FCM
Background: CD45RA is a 205-220 kD single chain type I glycoprotein. It is an exon 4 splice variant of the tyrosine phosphatase CD45. The CD45RA isoform is expressed on resting/naïve T cells, medullary thymocytes, B cells and monocytes. CD45RA enhances both T cell receptor and B cell receptor signaling. CD45 non-covalently associates with lymphocyte phosphatase-associated phosphoprotein (LPAP) on T and B lymphocytes. CD45 has been reported to be associated with several other cell surface antigens including CD1, CD2, CD3, and CD4. CD45 has also been reported to bind galectin-1. CD45 isoform expression can change in response to cytokines.
Concentration: N/A
Conjugation: AF488
Buffer: PBS with 0.05% Proclin300, 1% BSA
Isotype: Mouse IgG2b, κ
Storage: Store at 2~8°C and protected from prolonged exposure to light. Do not freeze.
