Description
AF/LE Purified Anti-Mouse CD45.2 Antibody | DL21519F-3 | Gentaur US, UK & Europe Disrtribition
Synonyms: Ly-5.2, LCA
Reactivity: Mouse
Host: Mouse
Application: Block,FCM
Background: CD45.2 is an alloantigen of CD45, expressed by Ly5.2 bearing mouse strains (e.g., A, AKR, BALB/c, CBA/Ca, CBA/J, C3H/He, C57BL, C57BR, C57L, C58, DBA/1, DBA/2, NZB, SWR, 129) . CD45, a member of the protein tyrosine phosphatase (PTP) family, is a 180-240 kD glycoprotein expressed on all hematopoietic cells except mature erythrocytes and platelets. There are multiple isoforms in the mouse that play key roles in TCR and BCR signal transduction. These isoforms are very specific to the activation and maturation states of the cell as well as specific cell type. The primary ligands for CD45 are galectin-1, CD2, CD3, CD4, TCR, CD22, and Thy-1.
Concentration: 0.5 mg/mL
Conjugation: None (Purified antibody-Azide Free/Low endotoxin)
Buffer: 0.2 μm filtered in PBS, pH7.2. Azide Free (AF) /Low Endotoxin (LE) : Contains no stabilizers or preservatives. Endotoxin level is < 2 EU/mg as Determined by LAL gel clotting assay.
Isotype: Mouse IgG2a, κ
Storage: Store at 2~8°C. Do not freeze.
