Description
AF/LE Purified Anti-Human/Mouse/Rat CD47 Antibody | DL20293F-3 | Gentaur US, UK & Europe Disrtribition
Synonyms: Leukocyte surface antigen CD47,Cd47,Integrin-associated protein,IAP
Reactivity: Human,Mouse,Rat
Host: Mouse
Application: FCM
Background: CD47, also known as Integrin-Associated Protein (IAP), is a membrane protein of about 50 kD with an IgV-like extracelluluar domain, a five membrane-spanning segment and a short terminal cytoplasmic region. It is widely expressed on many cell types and often associated with beta 3 integrins. It has been reported that CD47 functions as a self marker. Red cells lacking CD47 were rapidly cleared from the bloodstream by splenic macrophages. By binding to SIRPα, CD47 controls hemostatic innate immune functions, such as phagocytosis and cell trafficking.
Concentration: 0.5 mg/mL
Conjugation: None (Purified antibody-Azide Free/Low endotoxin)
Buffer: 0.2 μm filtered in PBS, pH7.2. Azide Free (AF) /Low Endotoxin (LE) : Contains no stabilizers or preservatives. Endotoxin level is < 2 EU/mg as Determined by LAL gel clotting assay.
Isotype: Mouse IgG1, κ
Storage: Store at 2~8°C. Do not freeze.
