Description
AF/LE Purified Anti-Human/Monkey CD154 Antibody | DL21618F-2 | Gentaur US, UK & Europe Disrtribition
Synonyms: CD40L, gp39, TRAP, T-BAM, TNFSF5
Reactivity: Human,Monkey
Host: Mouse
Application: Block,FCM
Background: CD154 (CD40 ligand) is also known as CD40L, gp39, TRAP and T-BAM. CD40 ligand is a 32-39 kD type II transmembrane glycoprotein. It is a member of the TNF superfamily and is expressed on activated T cells. It has been reported to be important for B cell costimulation following binding of its receptor, CD40. Additionally, binding of CD40L to CD40 on B cells promotes the secretion of immunoglobulin and Ig isotype switching. CD40L is also involved in the regulation of cytokine production by T cells.
Concentration: 0.5 mg/mL
Conjugation: None (Purified antibody-Azide Free/Low endotoxin)
Buffer: 0.2 μm filtered in PBS, pH7.2. Azide Free (AF) /Low Endotoxin (LE) : Contains no stabilizers or preservatives. Endotoxin level is < 2 EU/mg as Determined by LAL gel clotting assay.
Isotype: Mouse IgG2a, κ
Storage: Store at 2~8°C. Do not freeze.
