Description
ADAMTS4 Antibody | R30551 | Gentaur US, UK & Europe Disrtribition
Family: Primary antibody
Formulation: 0.5mg/ml if reconstituted with 0.2ml sterile DI water
Format: Antigen affinity purified
Clone: N/A
Host Animal: Rabbit
Clonality: Polyclonal (rabbit origin)
Species Reactivity: Human, Mouse, Rat
Application: WB
Buffer: N/A
Limitation: This ADAMTS4 antibody is available for research use only.
Purity: Antigen affinity
Description: 'A disintegrin and metalloproteinase with thrombospondin motifs 4' is an enzyme that in humans is encoded by the ADAMTS4 gene. It is a member of the large ADAMTS family of zinc-dependent proteases. The human ADAMTS4 gene is mapped to chromosome 1 by somatic cell hybrid analysis. The enzyme encoded by this gene lacks a C-terminal TS motif. It is responsible for the degradation of aggrecan, a major proteoglycan of cartilage, and brevican, a brain-specific extracellular matrix protein. The cleavage of aggrecan and brevican suggests key roles of this enzyme in arthritic disease and in the central nervous system, potentially, in the progression of glioma.
Immunogen: An amino acid sequence from the C-terminus of human ADAMTS4 (RRAQILEILRRRPWAGRK) was used as the immunogen for this ADAMTS4 antibody.
Storage: After reconstitution, the ADAMTS4 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20 °C. Avoid repeated freezing and thawing.
