ACR Antibody / Acrosin | F51511-0.08ML

ACR Antibody / Acrosin | F51511-0.08ML | Gentaur US, UK & Europe Disrtribition

Family: Primary antibody

Formulation: In 1X PBS, pH 7.4, with 0.09% sodium azide

Format: Purified

Clone: N/A

Host Animal: Rabbit

Clonality: Polyclonal (rabbit origin)

Species Reactivity: Human

Application: WB, IHC, FACS, ELISA

Buffer: N/A

Limitation: This ACR antibody is available for research use only.

Purity: Purified

Description: Acrosin is the major proteinase present in the acrosome of mature spermatozoa. It is a typical serine proteinase with trypsin-like specificity. It is stored in the acrosome in its precursor form, proacrosin. The active enzyme functions in the lysis of the zona pellucida, thus facilitating penetration of the sperm through the innermost glycoprotein layers of the ovum. The mRNA for proacrosin is synthesized only in the postmeiotic stages of spermatogenesis. In humans proacrosin first appears in the haploid spermatids.

Immunogen: A portion of amino acids 99-127 from the human protein was used as the immunogen for this ACR antibody.

Storage: Aliquot the ACR antibody and store frozen at -20 °C or colder. Avoid repeated freeze-thaw cycles.