Description
ACN9 Antibody / SDHAF3 | F41148-0.4ML | Gentaur US, UK & Europe Disrtribition
Family: Primary antibody
Formulation: In 1X PBS, pH 7.4, with 0.09% sodium azide
Format: Antigen affinity purified
Clone: N/A
Host Animal: Rabbit
Clonality: Polyclonal (rabbit origin)
Species Reactivity: Human, Mouse
Application: WB, IHC, ELISA
Buffer: N/A
Limitation: This ACN9 antibody is available for research use only.
Purity: Antigen affinity
Description: ACN9/SDHAF3 plays an essential role in the assembly of succinate dehydrogenase (SDH), an enzyme complex (also referred to as respiratory complex II) that is a component of both the tricarboxylic acid (TCA) cycle and the mitochondrial electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Promotes maturation of the iron-sulfur protein subunit SDHB of the SDH catalytic dimer, protecting it from the deleterious effects of oxidants. May act together with SDHAF1. [UniProt]
Immunogen: A portion of amino acids 13-42 from the human protein was used as the immunogen for this ACN9 antibody.
Storage: Aliquot the ACN9 antibody and store frozen at -20 °C or colder. Avoid repeated freeze-thaw cycles.
