Description
ACK1 Antibody / Activated CDC42 kinase 1 | F50698-0.08ML | Gentaur US, UK & Europe Disrtribition
Family: Primary antibody
Formulation: In 1X PBS, pH 7.4, with 0.09% sodium azide
Format: Purified
Clone: N/A
Host Animal: Rabbit
Clonality: Polyclonal (rabbit origin)
Species Reactivity: Human, Mouse
Application: WB, IHC, ELISA
Buffer: N/A
Limitation: This ACK1 antibody is available for research use only.
Purity: Purified
Description: Activated CDC42 kinase 1 is a tyrosine kinase that binds Cdc42Hs in its GTP-bound form and inhibits both the intrinsic and GTPase-activating protein (GAP)-stimulated GTPase activity of Cdc42Hs. This binding is mediated by a unique sequence of 47 amino acids C-terminal to an SH3 domain. The protein may be involved in a regulatory mechanism that sustains the GTP-bound active form of Cdc42Hs and which is directly linked to a tyrosine phosphorylation signal transduction pathway.
Immunogen: A portion of amino acids 934-964 from the human protein was used as the immunogen for this ACK1 antibody.
Storage: Aliquot the ACK1 antibody and store frozen at -20 °C or colder. Avoid repeated freeze-thaw cycles.
