Aciculin Antibody / Phosphoglucomutase 5 | V8411SAF-100UG

Aciculin Antibody / Phosphoglucomutase 5 | V8411SAF-100UG | Gentaur US, UK & Europe Disrtribition

Family: Primary antibody

Formulation: 1 mg/ml in 1X PBS; BSA free, sodium azide free

Format: Purified

Clone: 14F8/F8

Host Animal: Mouse

Clonality: Monoclonal (mouse origin)

Species Reactivity: Human

Application: WB, IHC-P

Buffer: N/A

Limitation: This Aciculin antibody is available for research use only.

Purity: Protein G affinity chromatography

Description: Aciculin, also known as PGM5 (phosphoglucomutase 5) or PGMRP, is a 567 amino acid protein that belongs to the phosphoglucomutase family of phosphotransferases, which play an important role in the interconversion of glucose-1-phosphate and glucose-6-phosphate. Localized to the cell junction and expressed at high levels in smooth and cardiac muscle, Aciculin binds magnesium as a cofactor and interacts with dystrophin and utrophin, possibly playing a role in cytoskeletal organization and function. Aciculin exists as two alternatively spliced isoforms and is encoded by a gene that maps to human chromosome 9, which houses over 900 genes and comprises nearly 4% of the human genome.

Immunogen: The cytoskeletal fraction of the human myometrium tissue extract was used as the immunogen for the Aciculin antibody.

Storage: Store the Aciculin antibody at 2-8oC (with azide) or aliquot and store at -20 °C or colder (without azide).