Description
AChR Antibody (nicotinic) | R30303 | Gentaur US, UK & Europe Disrtribition
Family: Primary antibody
Formulation: 0.5mg/ml if reconstituted with 0.2ml sterile DI water
Format: Antigen affinity purified
Clone: N/A
Host Animal: Rabbit
Clonality: Polyclonal (rabbit origin)
Species Reactivity: Human, Mouse, Rat
Application: WB
Buffer: N/A
Limitation: This AChR antibody is available for research use only.
Purity: Antigen affinity
Description: AChR alpha, also called CHRNA, is mapped on 2q24-q32. This gene encodes the alpha subunit of the muscle acetylcholine receptor, which is the main target of pathogenic autoantibodies in autoimmune myasthenia gravis. The protein-coding sequence of the human alpha subunit gene is divided into 9 exons that correspond to different structural and functional domains of the precursor molecule.
Immunogen: Amino acids 22-36 (EHETRLVAKLFKDYS) from the alpha subunit were used as the immunogen for this nicotinic AChR antibody (100% homologous in human and rat).
Storage: Store the lyophilized AChR antibody at 4oC. After reconstitution, aliquot and store at -20 °C. Avoid repeated freezing and thawing.
