ACE Antibody / Angiotensin I Converting Enzyme | V8490SAF-100UG

ACE Antibody / Angiotensin I Converting Enzyme | V8490SAF-100UG | Gentaur US, UK & Europe Disrtribition

Family: Primary antibody

Formulation: 1 mg/ml in 1X PBS; BSA free, sodium azide free

Format: Purified

Clone: ACE/3762

Host Animal: Mouse

Clonality: Monoclonal (mouse origin)

Species Reactivity: Human

Application: WB, ELISA, IHC-P

Buffer: N/A

Limitation: This ACE antibody is available for research use only.

Purity: Protein G affinity chromatography

Description: This gene encodes an enzyme involved in catalyzing the conversion of angiotensin I into a physiologically active peptide angiotensin II. Angiotensin II is a potent vasopressor and aldosterone-stimulating peptide that controls blood pressure and fluid-electrolyte balance. This enzyme plays a key role in the renin-angiotensin system. Many studies have associated the presence or absence of a 287 bp Alu repeat element in this gene with the levels of circulating enzyme or cardiovascular pathophysiologies. Two most abundant alternatively spliced variants of this gene encode two isozymes - the somatic form and the testicular form that are equally active. Multiple additional alternatively spliced variants have been identified but their full length nature has not been determined.

Immunogen: A portion of amino acids 652-788 from the human protein was used as the immunogen for the ACE antibody.

Storage: Store the ACE antibody at 2-8oC (with azide) or aliquot and store at -20 °C or colder (without azide).