ACE Antibody / Angiotensin-Converting Enzyme | RQ5388

ACE Antibody / Angiotensin-Converting Enzyme | RQ5388 | Gentaur US, UK & Europe Disrtribition

Family: Primary antibody

Formulation: Antibody in PBS with 0.02% sodium azide and 50% glycerol

Format: Purified

Clone: ADCO-1

Host Animal: Rabbit

Clonality: Rabbit Monoclonal

Species Reactivity: Human, Mouse

Application: WB

Buffer: N/A

Limitation: This ACE antibody is available for research use only.

Purity: Affinity purified

Description: The ACE gene encodes an enzyme involved in catalyzing the conversion of angiotensin I into a physiologically active peptide angiotensin II. Angiotensin II is a potent vasopressor and aldosterone-stimulating peptide that controls blood pressure and fluid-electrolyte balance. This enzyme plays a key role in the renin-angiotensin system. Many studies have associated the presence or absence of a 287 bp Alu repeat element in this gene with the levels of circulating enzyme or cardiovascular pathophysiologies. Multiple alternatively spliced transcript variants encoding different isoforms have been identified, and two most abundant spliced variants encode the somatic form and the testicular form, respectively, that are equally active. [RefSeq]

Immunogen: A synthetic peptide specific to human Angiotensin-Converting Enzyme was used as the immunogen for the ACE antibody.

Storage: Store the ACE antibody at -20 °C.