Description
ABT-888 (Veliparib) | 27101 | Gentaur US, UK & Europe Disrtribition
Category: PARP/Inhibitors / Activators
Application: N/A
Background: N/A
Description: ABT-888 (Veliparib) is a potent inhibitor of both PARP-1 and PARP-2. In the MX-1 breast xenograft model (BRCA1 deletion and BRCA2 mutation), ABT-888 potentiated cisplatin, carboplatin, and cyclophosphamide, causing regression of established tumors, whereas with comparable doses of cytotoxic agents alone, only modest tumor inhibition was exhibited.
Product Type: Inhibitor
Shippement Condition: -20°C
