ABO Antibody (Blood Group Antigen H Type 2) | V8857SAF-100UG

ABO Antibody (Blood Group Antigen H Type 2) | V8857SAF-100UG | Gentaur US, UK & Europe Disrtribition

Family: Primary antibody

Formulation: 1 mg/ml in 1X PBS; BSA free, sodium azide free

Format: Purified

Clone: A51-B/A6

Host Animal: Mouse

Clonality: Monoclonal (mouse origin)

Species Reactivity: Human

Application: IF, IHC-P

Buffer: N/A

Limitation: This Blood Group H2 antibody is available for research use only.

Purity: Protein affinity

Description: This antibody reacts with H type 2 blood group epitope Fuca1-2 Galb1-4 GlcNAc. It does not cross-react with human blood group H type 1, 3 or 4, nor with the closely related type 2 antigen Ley and Lex. Blood-group antigens are generally defined as molecules formed by sequential addition of saccharides to the carbohydrate side chains of lipids and proteins detected on erythrocytes and certain epithelial cells. The A, B and H antigens are reported to undergo modulation during malignant cellular trans- formation. Blood group related antigens are usually mucin-type and are detected on erythrocytes, certain epithelial cells and in secretions of certain individuals. Sixteen genetically and biosynthetically distinct but inter-related specificities belong to this group of antigens, including A (1 and 2), B, H (1 and 2), M, N, Lewis A, Lewis B, Lewis X, Lewis Y and precursor type 1 chain antigens. The expressions of the H1 and H2 in different cell types are con- trolled by different genes.

Immunogen: Human breast cancer MCF-7 cells were used as the immunogen for the Blood Group H2 antibody. This antibody reacts with H type 2 blood group epitope Fuca1-2 Galb1-4 GlcNAc.

Storage: Aliquot the Blood Group H2 antibody and store frozen at -20 °C or colder. Avoid repeated freeze-thaw cycles.