Description
ABCG2 Polyclonal Antibody | E-AB-30393 | Gentaur US, UK & Europe Disrtribition
Reactivity: Human
Host: Rabbit
Isotype: IgG
Application: WB, IHC-p, ELISA
Research Area: Cancer, Metabolism, Signal Transduction, Stem Cells, Tags and Cell Markers
Background: Xenobiotic transporter that may play an important role in the exclusion of xenobiotics from the brain. May be involved in brain-to-blood efflux. Appears to play a major role in the multidrug resistance phenotype of several cancer cell lines. When overexpressed, the transfected cells become resistant to mitoxantrone, daunorubicin and doxorubicin, display diminished intracellular accumulation of daunorubicin, and manifest an ATP-dependent increase in the efflux of rhodamine 123.
Lead Time: 7~10 days
Concentration: 1 mg/mL
Storage: Store at -20°C. Avoid freeze / thaw cycles.
Immunogen: Synthesized peptide derived from the Internal region of human ABCG2.
Buffer: PBS with 0.02% sodium azide, 0.5% BSA and 50% glycerol, pH7.4
Purification: Affinity purification
Dilution: WB 1:500-1:2000, IHC 1:100-1:300, ELISA 1:10000
Conjugation: Unconjugated
Calculated Molecular Weight: 72 kDa
Observed Molecular Weight: 72 kDa
Clonality: Polyclonal
