ABCG2 Polyclonal Antibody | E-AB-30393

ABCG2 Polyclonal Antibody | E-AB-30393 | Gentaur US, UK & Europe Disrtribition

Reactivity: Human

Host: Rabbit

Isotype: IgG

Application: WB, IHC-p, ELISA

Research Area: Cancer, Metabolism, Signal Transduction, Stem Cells, Tags and Cell Markers

Background: Xenobiotic transporter that may play an important role in the exclusion of xenobiotics from the brain. May be involved in brain-to-blood efflux. Appears to play a major role in the multidrug resistance phenotype of several cancer cell lines. When overexpressed, the transfected cells become resistant to mitoxantrone, daunorubicin and doxorubicin, display diminished intracellular accumulation of daunorubicin, and manifest an ATP-dependent increase in the efflux of rhodamine 123.

Lead Time: 7~10 days

Concentration: 1 mg/mL

Storage: Store at -20°C. Avoid freeze / thaw cycles.

Immunogen: Synthesized peptide derived from the Internal region of human ABCG2.

Buffer: PBS with 0.02% sodium azide, 0.5% BSA and 50% glycerol, pH7.4

Purification: Affinity purification

Dilution: WB 1:500-1:2000, IHC 1:100-1:300, ELISA 1:10000

Conjugation: Unconjugated

Calculated Molecular Weight: 72 kDa

Observed Molecular Weight: 72 kDa

Clonality: Polyclonal