Description
ABCG2 Antibody (BCRP) | R30969 | Gentaur US, UK & Europe Disrtribition
Family: Primary antibody
Formulation: 0.5mg/ml if reconstituted with 0.2ml sterile DI water
Format: Antigen affinity purified
Clone: N/A
Host Animal: Rabbit
Clonality: Polyclonal (rabbit origin)
Species Reactivity: Mouse, Rat
Application: WB
Buffer: N/A
Limitation: This ABCG2 antibody is available for research use only.
Purity: Antigen affinity
Description: ABCG2 (ATP-binding cassette, subfamily G, member 2) also known as ABCP, BCRP (Breast cancer resistance protein) or MRX (Mitoxantrone resistance-associated protein), is a protein that in humans is encoded by the ABCG2 gene. The gene encodes a membrane transporter belonging to the ATP-binding cassette (ABC) superfamily of membrane transporters, which are involved in the trafficking of biologic molecules across cell membranes.The protein is also a high capacity transporter for uric acid excretion in the kidney, liver, and gut. In vitro assays of isolated membrane preparations revealed a high-capacity, vanadate-sensitive ATPase activity associated with ABCG2 expression that was stimulated by compounds known to be transported by this protein.
Immunogen: Amino acids 152-167 (KNHEKNERINTIIKEL-mouse) were used as the immunogen for this BCRP / ABCG2 antibody.
Storage: The lyophilized ABCG2 antibody can be stored at 4oC to -20 °C. After reconstitution, aliquot and store at -20 °C. Avoid repeated freezing and thawing.
