Description
ABCG2 Antibody (BCRP) | F44284-0.08ML | Gentaur US, UK & Europe Disrtribition
Family: Primary antibody
Formulation: In 1X PBS, pH 7.4, with 0.09% sodium azide
Format: Purified
Clone: N/A
Host Animal: Rabbit
Clonality: Polyclonal (rabbit origin)
Species Reactivity: Human
Application: WB, IF, FACS, IHC, ELISA
Buffer: N/A
Limitation: This ABCG2 antibody is available for research use only.
Purity: Purified
Description: ABCG2 is a membrane-associated protein included in the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the White subfamily. Alternatively referred to as a breast cancer resistance protein, this protein functions as a xenobiotic transporter which may play a major role in multi-drug resistance. It likely serves as a cellular defense mechanism in response to mitoxantrone and anthracycline exposure. Significant expression of this protein has been observed in the placenta, which may suggest a potential role for this molecule in placenta tissue.
Immunogen: A portion of amino acids 305-335 from the human protein was used as the immunogen for this ABCG2 antibody.
Storage: Aliquot the ABCG2 antibody and store frozen at -20 °C or colder. Avoid repeated freeze-thaw cycles.
