Description
AAV1 Luciferase-eGFP | 78461 | Gentaur US, UK & Europe Disrtribition
Category: Viral Tools/AAV
Application: Use as a positive control for transduction Optimize transduction assays and track expression over time
Background: N/A
Description: Adeno-Associated Virus Serotype 1 (AAV1) exhibits high homology with other AAV serotypes. AAV1 efficiently transduces muscle tissue, as determined by a region of the capsid protein VP1 (amino acids 350 to 430) which functions as a major determinant of tissue tropism. These AAV1 particles constitutively express the firefly (Photinus pyralis) luciferase and eGFP genes connected via a T2A linker, under the control of a CMV promoter. The T2A self-cleaving peptide (derived from Thosea asigna virus 2A) leads to the efficient cleavage of the transcript, and expression of luciferase and eGFP as two separate proteins.
Product Type: AAV virus
Shippement Condition: -80°C
