Description
14-3-3 zeta Protein, His-tag (Human) | 79039 | Gentaur US, UK & Europe Disrtribition
Category: Kinase/Kinase Substrates
Application: Western blot
Background: 14-3-3 zeta (also known as tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide) is a member of the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. 14-3-3 zeta protein plays a key role in cancer biology by being an important regulator of major cellular processes such as proliferation, differentiation, senescence and apoptosis (1). 14-3-3 zeta protein has been shown to interact with the IRS1 protein, suggesting a role for this protein in regulating insulin sensitivity by interrupting the association between the insulin receptor and IRS1 (2).
Description: Human 14-3-3 zeta Protein, GenBank Accession No. NM_012479, full length, with N-terminal His-tag, expressed in Sf9 insect cells using baculovirus. MW = 31 kDa.
Product Type: Protein
Shippement Condition: -80°C
