Description
14-3-3 theta Protein, His-tag (Human) | 79038 | Gentaur US, UK & Europe Disrtribition
Category: Kinase/Kinase Substrates
Application: Western blot
Background: 14-3-3 theta (also known as tyrosine 3-monooxygenase /tryptophan 5-monooxygenase activation protein, theta polypeptide) is a member of the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. Through interaction with ASK1, c-jun NH-terminal kinase, and p38 mitogen-activated protein kinase (MAPK), 14-3-3 theta plays an important role in controlling apotopsis (1). Induced expression of 14-3-3 theta protein has been reported in patients with amyotrophic lateral sclerosis. Additionally, 14-3-3 theta has been observed to mediate nucleo-cytoplasmic shuttling of the N protein (coronavirus nucleocapsid protein) which causes severe acute respiratory syndrome (2).
Description: Human 14-3-3 theta Protein, GenBank Accession No. NM_006826, full length, with N-terminal His-tag, expressed in Sf9 insect cells using baculovirus. MW = 30 kDa.
Product Type: Protein
Shippement Condition: -80°C
