Description
14-3-3 epsilon Antibody / YWHAE | V7362-20UG | Gentaur US, UK & Europe Disrtribition
Family: Primary antibody
Formulation: 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide
Format: Purified
Clone: CPTC-YWHAE-1
Host Animal: Mouse
Clonality: Monoclonal (mouse origin)
Species Reactivity: Human
Application: WB, IHC-P
Buffer: N/A
Limitation: This 14-3-3 epsilon antibody is available for research use only.
Purity: Protein G affinity chromatography
Description: Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathway. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner. It interacts with CDC25 phosphatases, RAF1 and IRS1 proteins, suggesting its role in diverse biochemical activities related to signal transduction, such as cell division and regulation of insulin sensitivity. It has also been implicated in the pathogenesis of small cell lung cancer. The YWHAE gene which encodes 14-3-3 epsilon has also been identified as a possible susceptibility gene for schizophrenia.
Immunogen: Full length recombinant human protein was used as the immunogen for the 14-3-3 epsilon antibody.
Storage: Store the 14-3-3 epsilon antibody at 2-8oC (with azide) or aliquot and store at -20 °C or colder (without azide).
