Description
14-3-3 beta/alpha Antibody / YWHAB | F54967-0.08ML | Gentaur US, UK & Europe Disrtribition
Family: Primary antibody
Formulation: In 1X PBS, pH 7.4, with 0.09% sodium azide
Format: Purified
Clone: N/A
Host Animal: Rabbit
Clonality: Polyclonal (rabbit origin)
Species Reactivity: Human
Application: IF, WB, IHC-P
Buffer: N/A
Limitation: This YWHAB antibody is available for research use only.
Purity: Purified
Description: YWHAB belongs to the 14-3-3 family of proteins, members of which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals. The encoded protein has been shown to interact with RAF1 and CDC25 phosphatases, suggesting that it may play a role in linking mitogenic signaling and the cell cycle machinery. Two transcript variants differing in the 5' UTR, but encoding the same protein, have been identified for the gene. Both variants encode the same protein, however, they are differentially expressed in hematopoietic cells.
Immunogen: A portion of amino acids 217-246 from the human protein was used as the immunogen for the YWHAB antibody.
Storage: Aliquot the YWHAB antibody and store frozen at -20 °C or colder. Avoid repeated freeze-thaw cycles.
